Levente Deak
Al Zahra Hospital Dubai, UAE
Title: Rhinofacial conidiobolus coronatus fungal infection presenting as an intranasal tumor
Biography
Biography: Levente Deak
Abstract
Conidiobolomycosis is a rare form of zygomycosis infection and mostly found in the tropical rain forest areas. Our 42 years old male patient visited the middle part of the India for few days and 3 months later developed nasal blockage with severe epistaxis. He was seen initially in a primary care center and then referred to our hospital with the diagnosis of epistaxis and a suspected nasal tumor.rnCT and MRI reports confirmed the presence of a highly vascularized mass in the right nasal cavity. After surgical excision, the histopathology report confirmed Conidiobolus coronatus infection and granuloma formation with hyphae surrounded by an eosinophilic sheet (the Splendore-Hoeppli phenomenon). rnInitial treatment with Amphotericin B treatment was unsuccessful, and the infection progressed leading to both external and intranasal deformity. This necessitated further tumor mass excision and reconstruction. After receiving the antifungal susceptibility profile, a new combination therapy of itraconazole with fluconazole was started. Following 18 months of oral antifungal treatment, the disease was cured. rnFungal infection in the nose is commonly seen in immunocompromised or diabetic patients, however Conidiolomycosis infection has been mostly reported in healthy young adults presenting as nasal obstruction with facial swelling and massive nasal bleeding. With the advent of global travel today, this infection could potentially present anywhere.rnThe goal of this presentation is to put the Conidiobolomycosis infection into the differential diagnosis panel in the case of nasal obstruction
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