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Azza Al-Afify

Azza Al-Afify

King Saud Medical City, Kingdom of Saudi Arabia

Title: Antiphospholipid antibody syndrome with fatal multiple thrombi in the right atrium complicated with massive pulmonary embolism

Biography

Biography: Azza Al-Afify

Abstract

An emergency surgical intervention is a life saving procedure in antiphospholipid antibody syndrome with large right atrial (RA) thrombi complicated with a life threatening massive pulmonary emboli (PE). We are reporting a young lady died with a conservative treatment and refused the surgical intervention. Conservative treatment by thrombolytic therapy and anticoagulant has no role in the management of multiple inter-cardiac thrombi due to risk of recurrent embolization from these mobile large thrombi. In conclusion, antiphospholipid APL syndrome associated with high morbidity and mortality. The presence of mobile right atrial thrombi in patients with APL and pulmonary embolism portends poor prognosis with cardiopulmonary collapse due to PE. Therefore, treatment should be started immediately as any delay in administering therapy may be lethal. The optimal therapy remains controversial given absence of randomized trials