Saliha Chbicheb
Mohammed V University, Rabat-Morocco
Title: “Could the HHV8 induce the occurance of Kaposi Sarcoma?
Biography
Biography: Saliha Chbicheb
Abstract
Kaposi sarcoma (KS) is a multifocal angioproliferative disorder of vascular endothelium, usually described in HIV positif patients, and primarily affecting mucocutaneous tissues with the potential to involve viscera. Four clinical variants of classic, endemic, iatrogenic, and epidemic KS are described for the disease, each with its own natural history, site of predilection, and prognosis. All forms of Kaposi sarcoma may manifest in the oral cavity and Kaposi sarcoma–associated virus (KSHV), also known as Human Herpes Virus type 8, appears essential to development of all clinical variants. In the absence of therapy, the clinical course of KS varies from innocuous lesions seen in the classic variant to rapidly progressive and fatal lesions of epidemic KS. Our case report provides an overview of clinical aspects, pathogenesis and treatment about a non HIV positif patient presenting the classic form of KS related to HHV8